Intended use

This device is intended to be used for the in vitro quantitative determination of Procalcitonin (PCT) in human whole blood, serum or plasma. And it is for professional use only, not for self-testing of untrained individuals, nor for near-patient testing.

Summary

PCT is the prohormone of calcitonin, which consists of 116 amino acid residues and has a molecular weight of about 12.8 kD. It is a glycoprotein without hormone activity and an endogenous non-steroidal anti-inflammatory substance. It is produced by the thyroid in non-infectious situations. In systemic infections, especially bacterial infections, different types of cells in many organs are stimulated by proinflammatory responses to secrete PCT. PCT metabolism depends little on renal function and is not affected by steroid hormones. In clinical diagnosis, the level of PCT in patients with sepsis increased earlier, which is convenient for early diagnosis and monitoring by doctors. In the case of systemic infection, the PCT content in serum begins to increase within 2-4 hours, reaches a peak within 8-24 hours, and lasts for several days or weeks. When it is greater than a certain value, patients have the potential to develop severe sepsis and septic shock. In addition, PCT is an important marker that can specifically distinguish bacterial infection and inflammatory response caused by other reasons. Viral infection, allergy, autoimmune disease and transplant rejection will not cause a significant increase in PCT, while local bacterial infection can result in moderately elevated PCT levels. Therefore, PCT is an ideal indicator for the auxiliary diagnosis of severe bacterial infection, sepsis and other diseases, and has high sensitivity and specificity for systemic bacterial infection, sepsis, etc.

The current clinical methods for detecting PCT include chemiluminescence, immunochromatography and so on.

Hospitals

Laboratory

Clinics

Ambulance

Q: Are there any requirements for reagent storage?

A: The storage temperature of our reagents is room temperature, 2-30℃

Q: Reagent expiration date?

A: 12 months.

Q: Can I apply for free reagent samples?

A: Yes.

http://www.vacurebiotech.com/